For labs routinely measuring a large number of samples, sample throughput and the cost per sample are highly important. The experiment has studied the influence of various parameters on sample throughput while maintaining precision and accuracy. The robust and sensitive performance of the PlasmaQuant MS allows a reduction in scan rates resulting in increased sample throughput. The comparison shows that the high sensitivity allows an adjustment of the measurement speed which ultimately leads to more than 20% higher sample throughput. A method will be presented allowing for the analysis of more than 80 drinking water samples per hour according to regulations and methods like the US EPA 200.8 which specifies the criteria for drinking water analysis by means of ICP-MS. In this study, 21 elements (+3 internal standards) were measured over 7 hours with an average RSD of 2.2 %. Interferences were removed using the patented iCRC technology and quality control samples were measured to verify accuracy, precision, robustness of the method. The recovery rates of the quality control samples were between 90-105 % during the entire measurement and were evaluated fully automatically by the AspectMS software. The user friendly software, the lowest argon consumption on the market and the unmatched sensitivity result in the highest sample throughput and lowest cost per sample making the PQMS the ideal solution for labs measuring routinely a large number of samples.