Because of rapid industrialization and urbanization in China, large quantities of heavy metals have been discharged into the environment and caused serous soil pollution. Among the contaminants, cadmium (Cd) ranks the first in soil samples (7%) exceeding the limit. The availability of heavy metals, rather than the total concentration, posed environmental and human risks. Thus, this provide a strategy to remediation of heavy metals contaminated soils by immobilization, which transforms heavy metals into less bioavailable. In-situ immobilization is an inexpensive and effective solution for the remediation of extensively heavy metals contaminated soils. The immobilized metals may be released under different environmental stresses. However, most studies have focused on the influence of amendments on heavy metals availability and uptake by plants in a very short time. Therefore, it is essential to evaluation the sustainability of amendments under field conditions. In weak acid and Cd polluted soil (pH: 5.05, Cd: 0.56mg/kg), Jiangsu province, six alkaline materials were chosen as amendments and added to the soil in 2005. Through 10 years of continuous observation, the effectiveness of some materials was still considerable. The soil pH and CEC were remarkably increased by amendments at 1% dose. In contrast, the acid extractable Cd was significantly reduced. The Cd concentrations in Artemisia selengensis were compared in first, fifth and tenth year after amendment. The results showed that concentrations of Cd in A. selengensis were decreased with the increase of amount of amendments. The correlation analyses showed that the Cd concentrations in A. selengensis were significant negative with pH, CEC and bio-availability of Cd. It was noting that the Cd concentrations in A. selengensis were lower than limition at 1% addition (China Food Safety National Standard for Maximum Levels of Contaminants in Foods, GB 2762-2017), even ten years after amendment. Furthermore, no significant effects were found on biomass and the uptake of plant nutrition elements (K, Na, P, Ca, Mg). The selected materials combined with biochar were also used to remediate Cd polluted paddy soils in south China, Hunan (pH: 6.50, Cd: 0.45mg/kg) and Anhui (pH: 5.78, Cd: 2.3mg/kg). The results showed that composite passivators obviously reduced the bio-availability of Cd by increasing soil pH, CEC and OM, thereby decreased the uptake of Cd by rice. The Cd concentration in grains was reduced by more than 60% by the passivators and reached the limition. To our knowledge, this study was the longest evaluation of the effects of soil immobilization so far. The findings could be effectively and economically used for in situ remediation of heavy metals contaminated soils at a large scale.